Do Vaccines Affect Male Fertility?

In an effort to understand whether the BNT162b2 vaccine has a “possible detrimental impact on male fertility,” researchers at Tel Aviv University conducted a longitudinal study analyzing sperm volume and motility. While there have been some concerns expressed that the vaccines may impact reproductive organs, there was little to no systematic study of such a claim.

Study Objective

To investigate the effect of covid-19 BNT162b2 (Pfizer) vaccine on semen parameters among semen donors (SD).

Findings

This long-term study showed that while sperm count and motility were reduced within the first three months after vaccination, there was a recovery in those levels among sperm donors. An analysis performed at over 150 days after vaccination showed an overall recovery where semen volume and sperm motility were not impaired.

Limitations

No limitations were reported in this study. 

Implications

In relation to implications, the authors note that “Systemic immune response after BNT162b2 vaccine is a reasonable cause for transient semen concentration and TMC decline. Long-term prognosis remains good.”

Research Center Involved

Tel Aviv University, Israel

Key Investigators

Itai Gat, MD, Sperm Bank & Andrology Unit, IVF Department, Shamir Medical Center, Israel

Alon Kedem, Sackler Medical School, Tel Aviv University, Israel

Other investigators include Ana Umanski, Matan Levi, Ariel Hourvitz, and Micha Baum.

Telegram Channel

https://t.me/+LtveYCKl-JtlNzkx